The study isnt yet peer-reviewed, but it appears to show retatrutide leaving other GLP-1s in the dust: The highest dose made patients lose an average of 28% of their body mass after 80 weeks, running nearly a full lap around the highest dose of Novo Nordisks Wegovy (~15% weight loss after 68 weeks)
This body-composition profile is mechanistically consistent with GIPR-driven adipose lipolysis combined with the satiety-mediated caloric deficit, rather than generalized catabolism
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adults are considered obese
23 podcast episode, Brecka pressed Makary on how FDA policies might evolve with regard to a wide range of unapproved treatments and devices, including a blood filter, stem cells for type 1 diabetes, and peptides like BPC-157