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A recent study demonstrated the ability of a dendrimer-conjugated NAC (D-NAC) to specifically target glial and astrocyte cells, indicating potential to alter GSH levels in specific cell populations without altering levels throughout the CNS ( One of the most well-established properties of GSH is its role in maintaining redox homeostasis, but it is also emerging as a mediator of redox signaling through mechanisms such as protein S-glutathionylation and/or GSNO-mediated protein S-nitrosylation ( An emerging area of research is that of immune memory in the brain ( Because of the importance of GSH in many cellular and immunological processes and its potential as a biomarker, accurate measurement and analysis of GSH levels are critical to further research and analysis of its efficacy as a treatment

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