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By inhibiting the transfer of melanin to skin cells, niacinamide helps to gradually fade dark spots and prevent new pigmentation from forming

Epigallocatechin gallate (EGCG), a polyphenol in green tea, is also an allosteric inhibitor that competes with ADP [4]

However, current evidence is primarily derived from in vitro models or animal studies, and often relies on indirect indicators such as protein expression changes (e.g., LC3-II, Beclin-1)

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In a trial of adults with chronic sleep difficulties, consuming two kiwifruits 1 h before bedtime each night for 4 weeks led to significant improvements in sleep onset, duration, and efficiency