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The mimetics display profound anti-dementia and anti-PD activity, and herein are described methods for treating and/or preventing dementia and PD, and symptoms thereof, using the HGF minetics

Collectively, the evidence establishes MC4R agonists, particularly setmelanotide, as a promising therapeutic avenue for LRD, offering a targeted intervention where leptin-based therapies fail, though broader accessibility and further validation remain critical challenges

2 Both native highlanders and newcomers are at risk of high-altitude disease

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