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Figure 5 Since oxidative stress plays an important role in the pathogenesis of viral-associated cardiovascular and lung diseases, antioxidant intervention would be a rational approach to use for treating lower respiratory tract infections (Komaravelli and Casola, 2014) and balancing oxidative damage by enhancing antioxidant defense (Banjac et al., 2008
The day before the experiment, HEK293T cells were seeded in 96-well plates (8,000 cells/well)
Conversion of calcidiol to its biologically active form, calcitriol, occurs through the activity of a specific 25-hydroxyvitamin D 3 1--hydroxylase (commonly just called 1--hydroxylase) present in the inner mitochondrial membrane of cells of the proximal convoluted tubules of the kidneys, and in several extrarenal sites such as in keratinocytes, macrophages, and placenta