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Together, these findings suggest that KYN-driven oxidative stress is not merely an epiphenomenon of depression but a mechanistic contributor to mitochondrial dysfunction, neuroprogression, and systemic comorbidity, highlighting redox modulation as a critical interface between inflammation, KP activity, and depressive pathology

Nutrition 16:245254 Acknowledgments None

Cognitive Enhancer Supports synaptic connections and memory formation

Louveau, A

Many studies have shown that a deficit in glutathione is associated with psychopathology and clinical variables in schi-zophrenia.100101102 Mitochondrial dysfunction, which is closely associated with oxidative stress, is also associated with neurodegenerative change in schizophrenia