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A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid

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One full syringe

Inflammatory cytokines released by activated microglia and astrocytes (IL-1, TNF-, IL-6) upregulate the iron importer protein, DMT1, and downregulate the iron exporter protein, FPN1, promoting iron accumulation in neurons [179, 180]