The most common side effects were stomach issues like nausea, diarrhea, vomiting, reduced appetite, and constipation
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Additional risks include: Mental health effects : Phentermine may cause anxiety, restlessness, or insomnia, whilst mood changes have been reported with GLP-1 agonists Drug interactions : Phentermine should not be used with monoamine oxidase inhibitors (MAOIs) or other stimulants
This is what MDLs are for
In the pivotal SURPASS-2 trial (n=1,879), tirzepatide at all doses (5 mg, 10 mg, 15 mg) demonstrated both non-inferiority and superiority to semaglutide 1 mg injection for A1C reduction (-2.01% to -2.30% vs -1.86%) and body weight loss (-7.6 to -12.4 kg vs -5.7 kg)