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An alternative strategy is based on targeting tumor necrosis factor alpha (TNF-), a pro-inflammatory cytokine that has increased levels in AD

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They found that genetic knockdown of USP30 increased CNS mitophagy, protected against dopaminergic neuron loss, and reduced -synuclein aggregation

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According to a PubMed study, vitamin B12 deficiency can result from various factors, including poor absorption, issues with cellular delivery and uptake, and inadequate dietary intake