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Therefore, the authors hypothesized that the beneficial effect exerted by BMSCs in the nervous system might depend on HGF secretion and on HGF-MET axis activation (Song et al., 2020)

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These studies suggest that if this training routine (high volume or high intensity) is sustained for weeks, it will induce a sustained IS alteration, triggering a state of temporary immunosuppression in response to this type of PE training (Shaw et al., 2017)