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Age-related muscle loss (the progressive loss of skeletal muscle mass and strength) may increase the risk of falls and has been associated with increased mortality (Clynes, Calcif Tissue Int 2015)

Through initial SAR analysis based on their inhibitory effects against NO release in LPS-induced RAW264.7 cells, the optimal compound, 17 (Figure 17), demonstrated more potent anti-inflammatory activity than indomethacin and dexamethasone

J Biotechnol 290:1623

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