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Retatrutide is studied as a multi-receptor agonist targeting GIP, GLP-1, and glucagon receptors, and is used in laboratory research focused on complex metabolic signaling

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The standard cagrilintide monotherapy titration follows this schedule: 0.25 mg weekly for weeks 1-4, then 0.5 mg for weeks 5-8, then 1.0 mg for weeks 9-12, then 1.7 mg for weeks 13-16, and finally 2.4 mg for week 17 onward as the maintenance dose