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The primary source is related to the diet, including red meat

IGF-1 LR3 is legal to purchase as a research chemical for laboratory use onlyit is not FDA-approved for human consumption, cannot be legally sold as a dietary supplement under the Dietary Supplement Health and Education Act (DSHEA), and is banned by the World Anti-Doping Agency (WADA) for athletic use

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And the risks

Chronic Gut-Inflammation and Intestinal Barrier Dysfunction Impact the Status of Neurodegenerative Disorders Relevance to Irritable Bowel Disease Chronic GI inflammation increases the risk of PD (Lee et al., 2021a) and AD-dementia (Zhang et al., 2021)