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The effects on glucagon secretion are profound at both 3.5 and 12 mmol/l glucose, indicating that endogenous somatostatin is secreted and exerts paracrine effects at both low and high glucose, although somatostatin secretion is dependent on the prevailing glucose levels

Accessed 12/18/2013 at MNT

1 metabolism: Regulation by phase I and II metabolizing enzymes and chemoprotective agents

This integration can enhance ovarian cancer gene therapy from the following two perspectives: Capsid engineering for ovarian cancer stem cell-specific transduction Recent studies have demonstrated that AAV capsid engineering can enhance cancer cell-specific transduction efficiency [28, 80, 150,151,152], thereby increasing antitumor effects while reducing cytotoxicity to normal cells [153]

GIPR signaling in immune cells maintains metabolically beneficial type 2 immune responses in the white fat from obese mice