GLP-1 medications are synthetic versions of that hormone, engineered to last for a full week rather than fading within minutes
The investigators were blinded by which group of mice received a treatment and the vehicle, as injection was done by technicians from the Comparative Research Center of Rush University Medical Center
Morning dosing also aligns with natural cortisol rhythms
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Another ongoing trial will also investigate the effects of tirzepatide on CKD in patients with or without T2D, with a primary outcome of change in kidney oxygenation (TREASURE-CKD, NCT05536804) [71]