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In this study, we used a multi-omics approach to explore the functional changes and important mechanisms involved in severe IAV infection in T cells and finally reported our findings

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In total, more than 10,000 qualified cells per group were collected, cells of each group were randomly clustered into 23 subclusters and annotated into 9 major cell types, namely, granulosa cells (GCs), fibroblasts, theca cells, endothelial cells (ECs), ovarian surface epithelial cells (OSECs), oocytes, myeloid cells, erythrocytes, T and natural killer (NK) cells, and myeloid cells, among which T and NK cells and myeloid cells are immune cells (Fig