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Elevated Circulating Trimethylamine N-Oxide Levels Contribute to Endothelial Dysfunction in Aged Rats through Vascular Inflammation and Oxidative Stress

There is a risk that emphasizing pharmaceutical interventions may inadvertently reinforce harmful stereotypes about obesity being solely a medical problem rather than a complex condition influenced by genetic, environmental, and social factors

Cancer Cell 15 , 232239 (2009)

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In contrast, the combination of CB-839/telaglenastat with multiple tyrosine kinase receptor inhibitor cabozantinib did not improve the efficacy of cabozantinib in patients with advanced RCC in the CANTATA phase II randomized clinical trial (NCT03428217), although it was well tolerated [163]