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The injection is administered by a qualified healthcare professional and is especially beneficial for patients who cannot absorb vitamin B12 adequately from the digestive tract

Vitamin B12 can be converted to coenzyme B12 in tissues, and as such is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine, a reaction which also requires folate

Value-based healthcare models increasingly recognize the importance of clinical outcomes rather than simply drug acquisition costs

doi: 10.1002/mnfr.202000426 51 AlshahraniFAljohaniN

a , b ) Total dopamine content in the striatum of Trkb Penk-KO decreases significantly by 89 months of age (43%) after the initial increase at around three months (DA, 3.5 M vs 89 M, p = 0.007)