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In this context, several sensors and pathways regulating the transcription factors, such as activator protein 1 (AP-1), cAMP response element-binding protein (CREB), hypoxia inducible factor-1 (HIF-1), nuclear factor B (NF-B), activating transcription factor 4 (ATF-4), and nuclear factor-erythroid 2-related factor-2 (Nrf2), have been described (Marinho et al

Furthermore, the STRING database ( was used to analyze PPI network of GSH targets and the link of the genes was calculated by CytoHubba application in Cytoscape software

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[DOI] [PubMed] [Google Scholar] 117.Gallagher CM, Goodman MS