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Your physician reviews these factors before recommending a treatment plan, not the other way around

Receptor-mediated effects of glucocorticoids on inflammation: enhancement of the inflammatory response with a glucocorticoid antagonist

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doi: 10.1002/anie.202000451 281 TsangC

In hypoxia, succinate accumulation is observed, and restoration of Complex II activity through pure oxygen reperfusion induces rapid succinate oxidation met with an already abundant CoQH2 pool causing electrons to leak as reactive oxygen species (ROS) and free radical tissue damage to occur [36]