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NAD+ is studied as a longevity and cellular-energy research compound, focused on mitochondrial function and DNA-repair signaling

Get the details in the Quality Concerns section of our Cinnamon Supplements and Spices Review, which also identifies our Top Picks for ground cinnamon to avoid toxins

The compound was first reported in Al-Obeidi, Castrucci, Hadley, and Hruby, J Med Chem 32 (12):255561 (1989) (PMID 2555512), building on the earlier open-chain superpotent precursor [Nle, D-Phe]--MSH reported by Sawyer, Sanfilippo, Hruby, Engel, Heward, Burnett, and Hadley in PNAS 77 (10):57548 (1980) (PMID 6777774)

Free radicals are molecules that contain an uneven number of electrons and can cause oxidative stress, which is linked to many diseases such as cancer, diabetes, heart disease, and more

doi: 10.1093/brain/awh445 51 MurroughJWAbdallahCGMathewSJ