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Vasodilator nitrates, such as nitroglycerin, are metabolized to NO, which causes relaxation of vascular smooth muscle and, therefore, lowers blood pressure

However, taking more than 2,000 mg daily for extended periods is generally not recommended unless under direct medical supervision, as it could potentially lead to mineral imbalances or digestive discomfort

Its safety profile is comparable to a placebo, supporting its repurposing for ASD treatment [91]

It showed potential improvements for aromatase inhibitor-associated musculoskeletal symptoms, hot flashes, peripheral neuropathy and fatigue

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