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Environ Sci Pollut Res Int 29:3819838211

The products discussed are chemical reagents intended for laboratory research use only and are not intended for human use, diagnosis, treatment, cure, or prevention of any disease or medical condition

For example, ROS, via oxidation of thioredoxin, enhance the nuclear localization of both the ataxia-telangiectasia mutated (ATM) serine/threonine kinase, which is involved in DNA damage repair 31,32 , and redox factor-1 (Ref-1), a multifunctional protein that enables Fos/Jun DNA-binding and is identical to the apurinic/apyrimidinic 1 (APE1) endonuclease 33

The Journal Of Physiology