For people holding results without full titration
However, prescription GLP-1 medications come with considerations that do not work for everyone: they require injections, they require a prescription, they can cost over one thousand dollars per month without insurance, they have been subject to supply shortages, and they carry potential side effects that some people find difficult to tolerate
Clinical trial participants who took Zepbound lost an average of 50 pounds over 72 weeks, while those who took semaglutide, or Wegovy, lost about 33 pounds
Pinto-Lopes P, Afonso J, Pinto-Lopes R, et al
The most important difference is that Wegovy tablets must be taken on an empty stomach, whereas orforglipron can be taken with or without food