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In the hinge-latch hypothesis, the conformation of the Nrf2Keap1 complex is altered upon oxidative stress, implying that induction of target genes is only facilitated by newly synthesized Nrf2

Finally, we evaluate what can be learned from EPNs and plant-parasitic nematodes (PPNs) as models for mammalian-pathogenic nematodes to identify new parasite virulence and immunomodulatory molecules for immunotherapies and drug targets

Retrieved from National Institutes of Health Office of Dietary Supplements

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IF upregulate the brain-derived neurotrophic factor (BDNF), favoring neurogenesis, synaptic plasticity and mitochondrial biogenesis (Mattson et al., 2018)