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Targeting hif-1 signaling pathway for gastric cancer treatment
Previous studies have shown that plants can produce a series of stress responses to Cd pollution, including oxidative stress, an imbalance in enzymatic activity and plant signaling molecules (hormones and calcium ions), thus resulting in damage to the photosynthetic system, plasma membrane peroxidation, cell damage, changes in enzymatic activity, endoplasmic reticulum stress, protein degradation, or DNA damage or mutation
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As such, it does not support clinical recommendations for gaboxadol in FXS or broader ASD populations (154)
Several preclinical studies have investigated immediate and lasting effects of adverse early-life experience on hippocampal neurogenesis and the associated behavioral alterations using different models for ES [158]
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