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cruzi as a vaccine vector expressing a cancer-testis antigen (NY-ESO-1), a cancer vaccine candidate, which resulted in strong and long-term T-cell-mediated immunity and solid protection against melanoma in mice [278]

Most people begin to notice subtle improvements in skin brightness and tone within a few weeks of consistent use, but more noticeable effects typically require regular application for 812 weeks or longer

Takeaway: A highly specialized area of historical research with no current clinical application

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