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A delayed adverse drug effect or interaction could easily occur with vitamin B12 since the time necessary for most patients to become deficient can be delayed one or more years due to high storage levels in the body

doi: 10.2174/1573397113666170321120329

Chamayou AC, Neelakantan MA, Thalamuthu S, Janiak C: The first vitamin B 6 zinc complex, pyridoxinato-zinc acetate: a 1D coordination polymer with polar packing through strong inter-chain hydrogen bonding

These molds can produce mycotoxins, metabolites that are part of the fungis growth and can produce an immune-system response that triggers CIRS