Furthermore, the rising prevalence of obesity has significantly contributed to the growing utilization of GLP-1 analogs in the treatment of obesity, which is significantly driving the GLP-1 analogues market
Their nanoscale size allows them to cross the BBB and serve as natural carriers of bioactive molecules secreted by their parent cells or engineered drug delivery systems
Ninety-eight patients with obesity and MASLD (defined as 10% liver fat by MRI-PDFF) were contained in this substudy
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However, pharmacokinetic and physicochemical limitations such as poor solubility, low bioavailability, metabolic instability, and limited dermal targeting currently constrain clinical application
