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The nanosystem can release DOX by the low pH endosomes while up-taken by MDR/breast cancer cells and could silence the MDR1 gene and erythroblastosis virus E26 oncogene homolog 1 gene by MBs hybridizing with target sequences, plus it is capable of hindering DOX efflux transporter of P-glycoprotein expression and causing the progression of MDR breast cancer to desist

Reddys Laboratories Ltd aims to have about 15 GLP-1 drugs, used to treat obesity and diabetes, in its portfolio with various timelines, the pharma majors chief executive officer Erez Israeli said after the company announced its September quarter results on Tuesday

In contrast, untreated HepG2 ATP7B-KO cells were further separated from copper-treated HepG2 ATP7B-KO cells

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Safety: There is insufficient evidence regarding safety in humans