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Excessive lactate production during exercise increases the acidity of blood and tissue fluid, reduces ATP generation, and leads to fatigue

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The existing evidence is promising, but retatrutide should not be presented as an available clinical therapy until approved by regulatory agencies

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Intestinal absorption of carnitine and its renal reabsorption are mainly mediated by the plasma membrane organic cation transporter 2 (OCTN2SLC22A5), which has the highest affinity for carnitine among the carnitine handling transporters