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5 Recent literature, such as a review published in JAMA in May 2024, put the data from the WHI study into context by indicating that the study was primarily in women in late menopause (over the age of 60) and focused on HRT for chronic diseases such as cardiovascular disease or dementia rather than its utility for vasomotor symptoms

These findings reveal a novel mechanism for regulating ferroptosis and hold significant implications for developing treatments for ferroptosis-related diseases, such as cancer and ischemiareperfusion injury (67)

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Cai J, Kang Z, Liu WW, Luo X, Qiang S, Zhang JH, Ohta S, Sun X, Xu W, Tao H, Li R

& Galetti, V