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Such impairment in colonocyte function may promote Clostridium difficile infection (CDI).[236] PPIs and Immune Responses PPIs have also been shown to affect normal immune responses and clotting mechanisms

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Huang W, Liu Y, Luz A, Berrong M, Meyer JN, Zou Y, et al

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Furthermore, VEGF is believed to play a key role in traumatic brain injury (TBI), particularly in scenarios where Apolipoprotein E (ApoE) expression is absent (Genovese and Impellizzeri 2022)