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Autoimmunity (2020) 54(1):1322

Additional multi-agonist therapies (e.g., triple and higher-order receptor agonists) and expanded oral formulations are currently under investigation.[1] GLP-1 receptors are widely distributed in both central, vascular, and peripheral tissues, including regions of the brain involved in reward and motivation

This is when supplementation becomes most relevant

Their ability to mimic or inhibit specific protein functions makes them valuable tools in laboratories exploring both fundamental biology and experimental therapeutics

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