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But first came John Eng, MD, a researcher at the Veterans Affairs (VA) Medical Center in the Bronx, New York, whose interest in the Gila monster a type of lizard that can slow down its metabolism and maintain stable blood sugar levels even after long periods of not eatingled to a pretty big finding

CrossRef Decreased glomerular filtration rate and increased albuminuria for identification of cardiovascular autonomic neuropathy in subjects with and without diabetes Ying-Chuen Lai, Hung-Yuan Li, Yi-Dier Jiang, Tien-Jyun Chang, Lee-Ming Chuang Autonomic Neuroscience.2021

J Inherit Metab Dis 21(Suppl 1):151159

Metformin, originally prescribed for diabetic individuals, has been recognized for its significant cardiovascular protective properties

These new indications contributed to increased adoption among healthcare providers and patients