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(Source 2) Glutathione Deficiency and Disease Risk Glutathione is easily measured in red blood cells (erythrocytes)

ROS are key factors involved in the development and progression of various renal diseases, including ischemia-reperfusion (IR) injury, drug-induced acute kidney injury (AKI), chronic kidney disease (CKD), diabetic nephropathy (DN), hypertensive kidney damage, and other glomerular diseases [610]

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We thus conclude, that ROXY9 and maybe other class III GRXs will not efficiently take part in reactions on glutathione mixed disulfides unless the GSH scaffold site is altered by an induced fit of a specific substrate