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Expanding the therapeutic options for Candida infections using novel inhibitors of secreted aspartyl proteases

doi: 10.1186/s13072-016-0081-5 127 Vailati-RiboniM.ZhouZ.JacometoC

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Donath MY, Burcelin R

TB-500 contributes critical cytoskeletal and cellular migration mechanisms that enable fibroblasts to respond effectively to the synthetic and migratory signals provided by GHK-Cu and BPC-157. Research demonstrates that TB-500 treatment extends the anagen (growth) phase duration, increases cellular proliferation, and enhances the structural organization of newly synthesized ECM through its effects on actin dynamics and cellular mechanotransduction