Neuroepidemiology 46:144153 Wallin MT, Culpepper WJ, Nichols E, Bhutta ZA, Gebrehiwot TT, Hay SI, Khalil IA, Krohn KJ, Liang X, Naghavi M (2019) Global, regional, and national burden of multiple sclerosis 19902016: a systematic analysis for the global burden of disease study 2016
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Senescent cells secrete a toxic mix of inflammatory cytokines, proteases, and growth factors called the Senescence-Associated Secretory Phenotype (SASP)
100 l of a 0.2 mM peptide solution was injected intradermally into the back skin of mice following each IMQ treatment
The peptide stimulates the synthesis of chondroitin sulfate and decorin, two essential components of the cartilage matrix