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Front Neurosci 10:492

Costa, C., Moreira, J

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In children with ASD, studies have demonstrated that glutathione metabolism can be improved with subcutaneously injected methylcobalamin and oral folinic acid ( N -acetyl-l-cysteine, a supplement that provides a precursor to glutathione, was effective in improving symptoms and behaviors associated with ASD ( Small ( N -acetyl-l-cysteine ( Several other treatments that have antioxidant properties ( These studies suggest that treatments that address oxidative stress may improve core and associated symptoms of ASD

More recently, environmental pollutants including pesticides have been implicated in the pathogenesis of reproductive disorders [345, 346] and infertility