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How it was discovered: Scientists studying stomach ulcers noticed a particular protein sequence that protected the gut lining

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[7] [12] Women with pernicious anaemia , an autoimmune condition affecting B12 absorption, require ongoing B12 replacement therapy throughout pregnancy

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A study in Gut journal found T4 reduced collagen deposition and myofibroblast activation in chronic colitis models, suggesting it may prevent the structural complications (strictures, fistulas) that develop in long-standing diverticular disease