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From preclinical evidence to human studies: what makes a drug candidate ready for a First-in-Human trial

10.1186/s12610-017-0064-9 135

Optimal outcomes typically require consistent administration over months, allowing cellular glutathione stores to replenish and antioxidant defense systems to optimize

Their use should be limited to clear medical indicationstype 2 diabetes, obesity, insulin resistance, or elevated cardiometabolic riskand always integrated into a care plan that considers a womans reproductive goals, hormonal therapies, and individual symptom profile

Surely wed think it crazy if it was suddenly decided that just 4 doses of vitamin C a year cured scurvy