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It works primarily by improving cerebral blood flow and acting as an antioxidant

However, unlike GPx4, GPx7 does not contain a glutathione binding site (Pei et al

The catalase/peroxidase mutant was cultured for 90 min in the presence of 10 micromolar H 2 O 2 , a dose that was continuously sustained as described in Materials and methods

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J Am Soc Nephrol 30:18571869 Umekawa T, Hatanaka Y, Kurita T, Khan SR (2004) Effect of angiotensin II receptor blockage on osteopontin expression and calcium oxalate crystal deposition in rat kidneys