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The A-anticalin effect is not dependent on direct interaction with A monomers or dimers As an independent test for the anti-A action of the A-anticalin, we explored its effects on neuronal hyperactivity, which was experimentally induced through the direct application of A to the hippocampus of 24 month-old wild-type mice 10,18

More recently, emerging MRI techniques aimed at directly estimating extracellular pH have further expanded the potential to non-invasively characterise tumour acidity (194, 195), although these remain largely in the early stages of clinical validation

Can I skip the lower doses and start at a higher dose

You may experience some redness at the injection site, mild discomfort, and itching

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