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Researchers are still examining: Effects of taking these medications for decades Best maintenance strategies Long-term effects on muscle and bone health Whether lower maintenance doses work equally well Additional health benefits beyond diabetes and obesity As more long-term studies become available, recommendations may continue evolving

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The effect of glucagon-like peptide-1 receptor agonist therapy on body mass index in adolescents with severe obesity: a randomized, placebo-controlled, clinical trial

However, patients with severe renal impairment, type 1 diabetes, or recent pancreatitis should not use GLP-1 medications

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