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Retatrutide is a more recently developed investigational compound a triple agonist targeting the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors simultaneously
The molecular target that AOD-9604 actually binds is still unidentified, which the FDA explicitly noted in its December 2024 evaluation
AOD-9604 targets fat cells through selective activation of beta-3 adrenergic receptors on adipocytes, triggering lipolysis (fat breakdown) while simultaneously inhibiting lipogenesis (new fat formation)
On the other hand, Tirzepatide peptide may be used to influence biomarkers linked with type-2 diabetes or sugar control in research subjects