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A steady-state head-to-head pharmacokinetic comparison of all FK-506 (tacrolimus) formulations (ASTCOFF): an open-label, prospective, randomized, two-arm, three-period crossover study

4-6wks Typical cycle duration with proper medical monitoring and planned rest periods 1x/day Once-daily subcutaneous injection due to extended half-life Questions IGF-1 LR3 features a 13-amino acid N-terminal extension that extends its half-life from minutes to 20-30 hours and reduces binding to IGF binding proteins

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The compound is a non-natural or artificial protein