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For example, PPIs (proton pump inhibitors) such as Nexium, Prilosec OTC, etc., have detrimental effects on the gut microbiota due to gastric acid suppression, leading to unwanted overgrowths of pathogens like helicobactor pylori, clostridia, and contributing to many other undesired effects on human health mediated through alteration of the gastrointestinal microbiome
GRAND ROUNDS 23andMes New GLP-1 Service: Exploring Compounded Medications Were entering an era where GLP-1 medications have become the make-or-break factor for digital health companies as they rush to add these drugs to their weight management platforms to stay competitiveor face potential closure
Utilizing a mathematical model, the research examines how these interventions alter the bodys regulation of energy intake and expenditure, affecting the duration of effective weight loss
The key pathophysiologic mechanisms involved in MASH/MASLD, including nutrient-driven hepatic lipid accumulation, insulin resistance mediated increases in fatty acid flux, and activation of inflammatory and fibrogenic pathways