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It must be pointed out that the dose of Ex-4 administrated in the study (~400 mg/kg) was much higher than a clinical dose of Ex-4 taken by patients with T2DM (0.10.2 mg/kg)

doi: 10.1128/IAI.00095-21

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Phase 2 cagrilintide weight-management trial Review of cagrilintide and related safety data ClinicalTrials.gov cagrilintide study listings Cagrilintide side effects are best understood as a pattern: digestive symptoms are common, while dehydration, allergic symptoms, severe abdominal pain, or glucose problems need timely review

the remainder reaches the colon and may be fermented or excreted in faeces