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The primary mechanism involves slowing gastric emptyingthe rate at which food moves from your stomach into your small intestine

Moreover, we note that the LRC of GDH closed conformer includes approximately twofold more helical structures than its open form, making it much less flexible and potential for intense allosteric communication

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Common side effects include nausea, vomiting, and diarrhea, which are typically transient

Sustained ventricular tachycardia and ventricular fibrillation complicating non-ST-segment-elevation acute coronary syndromes. Circulation 126 (2012): 41-49