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47 In one small study of women who had undergone surgical menopause, just 30 days of estrogen therapy boosted their glutathione levelssuggesting that estrogen helps support the bodys antioxidant defenses

Despite its impressive benefits in the human body, glutathione is not useful as an oral supplement because it is inactivated by enzymes in the gut

All chronic diseases, including COVID-19 with the long-COVID-19-syndrome (271), are characterized by the presence of persistent chronic inflammation and sustained generation of reactive oxygen and nitrogen species that when confronted with inadequate antioxidant defenses (likely leading components of anti-inflammaging) precipitate excessive oxidative stress

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